Antibacterial efficacy in total safety

  • Description
  • Benefits
  • Indications
  • In Practice
  • FAQs
  • Evidence
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Adhesive lipido-colloid foam dressing impregnated with silver salts

Preventing and treating infection:

  • Broad spectrum antibacterial efficacy, including MRSA, when in contact with the wound bed
  • 99.9% removal of biofilm after 1 day (Pseudomonas aeruginosa, Staphylococcus aureus)
  • Pain-free dressing change
    + Absorption of moderate to high levels of exudate
    + Adhesive version for convenience

 

Pain-free and atraumatic dressing removal

A major benefit of TLC healing matrix (Technology Lipido-Colloid) is the non-adherence of the dressing which allows trauma-free removal from the newly-formed tissue with no pain for the patient.

Composition

UrgoCell Ag Border is an adhesive antibacterial foam dressing with TLC-Ag, comprised of:

  • A polyester mesh impregnated with petroleum jelly, hydrocolloid and silver particles combined with a polyurethane absorbent foam pad
  • A non-woven, semi-permeable polyurethane backing.

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Mode of action

When in contact with wound exudate, the TLC-Ag of UrgoCell Ag Border gels and creates a moist environment, promoting healing. This ensures non-adherence and pain-free dressing changes. When the silver salt is broken down in contact with the wound exudate, UrgoCell Ag Border acts as a reservoir capable of continuously releasing a bactericidal concentration of silver ions while in contact with the wound.

 

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This website is an international website. Some products or sizes can therefore be unavailable in some countries. For more information, please contact us.

Benefits for the wound

  • Broad spectrum antibacterial efficacy, including MRSA

  • 99.9% removal of biofilms within 1 day (Pseudomonas aeruginosa, Staphylococcus aureus)
  • Moist wound healing
  • Moderate to high absorbency
  • No adherence to the wound (no damage to newly formed tissue)
  • Protection of surrounding skin

benefits-for-professionnalBenefits for health professionals

  • Easy to apply
  • Easy to remove with pain-free dressing change
  • Exudate management (moderate to high absorbency)
  • Convenient (no need for secondary retention)
  • Can be used under compression

benefits-for-patientBenefits for patients

  • No adherence to the wound: pain-free dressing change
  • Well tolerated

UrgoCell Ag Border is indicated for the treatment of moderately to heavily exuding wounds with signs of local infection: chronic wounds (pressure sores and ulcers) and acute wounds (partial thickness burns, dermal abrasions, traumatic wounds, post-operative wounds, etc).

Due to the adhesive nature of the dressing, UrgoCell Ag Border is recommended for the treatment of wounds in which the surrounding skin is healthy.

Contraindications

Do not use when there is a known sensitivity to silver.
Do not use on patients undergoing Magnetic Resonance Imaging (MRI) examination.

Instructions for use

  • Clean the wound as per local protocol and rinse with normal saline.
  • If an antiseptic is first used, rinse the wound thoroughly with saline solution before applying UrgoCell Ag Border.
  • Dry the surrounding skin carefully.
  • Using the tabs, remove the protective film.
  • Apply UrgoCell Ag Border to the wound, by placing the central compress over it.
  • Apply compression bandage over the dressing when prescribed.
  • UrgoCell Ag Border should be changed every 1 to 3 days depending on the level of exudate and the clinical condition of the wound.

 

Precautions for use

  • As the lipido-colloïd layer of UrgoCell Ag Border adheres to surgical gloves (latex), it is recommended to manipulate the dressing avoiding contact with the coated layer.
  • Treatment with UrgoCell Ag Border should be carried out under medical supervision.
  • Concomitant use with other local treatments is not recommended.
  • Avoid contact of the dressing with electrodes or conductive gels used during EEG and ECG.
  • In the absence of any specific clinical data, use in pregnant or breast-feeding women, newborn and premature babies is not recommended.
  • Clinicians/healthcare professionals should be aware that there are very limited data on prolonged and repeated use of silver containing dressings, particularly in children and neonates.
  • Discard any unused parts of the dressing.
  • Check that the sterility protector is intact before use.
  • Single-use, individual and sterile dressing: re-using a single-use product may lead to risks of infection.
  • Do not re-sterilise the dressing.

urgocell_ag_border_13x13Size available

  • 10×10 cm

 

 

 


This website is an international website. Some products or sizes can therefore be unavailable in some countries. For more information, please contact us.

Product

What is UrgoCell Ag Border?

UrgoCell Ag Border is an antibacterial adhesive foam dressing with TLC-Ag, comprised of:

  • A polyester mesh impregnated with petroleum jelly, hydrocolloid and silver particles combined with a polyurethane absorbent foam pad
  • A non-woven, semi-permeable polyurethane backing.

How does UrgoCell Ag Border work?

When in contact with wound exudate, the TLC-Ag of UrgoCell Ag Border gels and creates a moist environment promoting healing. When the silver salt is broken down in contact with the wound exudate, UrgoCell Ag Border acts as a reservoir capable of continuously releasing a bactericidal concentration of silver ions while in contact with the wound.

Is silver released into the wound bed to kill bacteria or are bacteria killed in contact with the dressing?

TLC Ag contains silver sulphate, whose antibacterial effect is only activated when in contact with wound exudate, the TLC creates a gel and the silver sulphate is transformed into silver ions and SO42-.
These Ag+ ions stay in the lipido-colloid gel and are not released in the wound bed.

What is the amount of silver required to kill pathogens?

It varies depending on the pathogen. However, the silver amount in the TLC gel is always greater than what is needed to kill 99,99% of the pathogen.
(according to an in vitro study : 7 days-8 tested bacteria)

Does silver go into the blood stream?

TLC Ag contains silver sulphate, whose antibacterial effect is only activated when in contact with wound exudate, the TLC creates a gel and the silver sulphate is transformed into silver ions and SO42-.
These Ag+ ions stay in the lipido-colloid gel, their antibacterial activity remains on the wound surface, and is not released in the wound bed, even less so at a systemic level.

Do silver dressings remove biofilms?

Yes. TLC-Ag dressings have been proven to be effective on biofilms. It was demonstrated in an in vitro study carried out on the biofilms of Staphylococcus aureus and Pseudomonas aeruginosa. After a day in contact with a TLC-Ag dressing, 99.97% and 99.98% of the biofilms were removed respectively.

The amount of silver in TLC-Ag products is low, are they as effective as other silver dressings? Do I need to change those more often?

In TLC Ag dressings, the Ag+ ions have a bactericidal effect with an amount of silver that is enough to be effective on the most resistant pathogens, for up to 7 days (in vitro).
Other dressings may require more silver to be effective as their mechanism of action is different. They quickly release silver and need to have a higher silver amount to be effective over time. This may represent a risk of reduced effectiveness.

Against which pathogens are the TLC-Ag dressings effective?

Ag ions’ mode of action is effective against a wide range of different pathogens. Tests have even been carried out on resistant pathogens, proving the efficacy of TLC-Ag.

TLC-Ag has a demonstrated antibacterial activity for up to 7 days on:

  • Methicillin-Resistant Staphylococcus aureus (MRSA)
  • Vancomycin-Resistant Enterococcus faecalis
  • Staphylococcus aureus
  • Pseudomonas aeruginosa
  • Streptococcus pyogenes
  • Escherichia coli
  • Candida albicans

Indications

When should I use UrgoCell Ag Border?

UrgoCell Ag Border is indicated for the treatment of moderately to heavily exuding wounds with signs of local infection.

Can I use UrgoCell Ag Border during the desloughing stage?

Yes, however, UrgoClean is the recommended treatment option for desloughing.

Can I use UrgoCell Ag Border with a gel?

Yes, it can be combined with a hydrogel.

What are the contraindications of UrgoCell Ag Border?

UrgoCell Ag Border should not be used where there is a known sensitivity to silver.
Do not use on patients undergoing Magnetic Resonance Imaging (MRI) examination.

Is there any adverse event related to Ag in the TLC-Ag products?

TLC Ag contains silver sulphate, whose antibacterial effect is only activated when in contact with wound exudate. These Ag+ ions stay in the lipido-colloïd geland are not released in the wound bed, preventing from argyrism or systemic toxicity.

Can I use TLC-Ag products in children?

No clinical studies have been carried out. However, TLC Ag has been widely used for the treatment of traumatic wounds and burns in children from the age of one.

Use

Can I use UrgoCell Ag Border under compression?

Yes.

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Cutting Guide

Can I cut UrgoCell Ag Border?

No. However, the adhesive edges can be cut if necessary to fit the dressing to different wound shapes.

How can I secure UrgoCell Ag Border?

Secure the dressing in place with a suitable bandage, adhesive tape, or apply a compression bandage when prescribed.

How long should I keep the dressing in place?

A maximum of four weeks use is recommended due to the good efficacy of TLC-Ag on most pathogens.
Dressing should be renewed every 1 to 3 days, depending on exudate level.

When should I stop using silver dressings and switch back to a neutral dressing?

A maximum of four weeks use is recommended due to the good efficacy of TLC-Ag on most pathogens.
If the wound evolves well before the end of the 4 weeks treatment, you can switch to a neutral dressing.

Evidence

What evidence do you have on TLC-Ag?

UrgoTul Ag/Silver is the only silver dressing which has been shown to be effective on wounds with signs of critical colonisation. The clinical study demonstrated that the use of UrgoTul Ag/Silver over 4 weeks followed by a neutral dressing (UrgoTul), reduced the size of the wound area faster than using a neutral dressing alone.

Why did you compare your silver dressing with a neutral one, rather than a silver dressing?

TLC-Ag was compared to the neutral TLC, in order to show the real effectiveness of silver.

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Supporting evidence-based practice: a clinical review of TLC technology    
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Last update : November 23, 2017